ABSTRACT
Objective To evaluate left ventricular myocardial systolic function in patients with obstructive sleep apnea hypopnea syndrome ( OSA HS) with normal left ventricular ejection fraction( LVEF) using three‐dimensional strain echocardiography . Methods One hundred patients with OSA HS were divided into mild group ,moderate group and severe group according to apnea hypopnea index ( A HI) w hile matched with 32 healthy people as control group . T he parameters such as three‐dimensional LVEF ,global longitudinal strain( GLS) ,global circumferential strain( GCS) ,global area strain( GAS) ,global radial strain ( GRS) ,twist and torsion based on standard three‐dimensional echocardiography were measured by three‐ dimensional strain echocardiography , the above parameters among the four groups were compared for difference .Linear correlationship between A HI ,LVEF and the three dimensional strain parameters was analyzed respectively . Results ①T here was no significant difference in three‐dimensional LVEF ,twist and torsion between each groups( P ＞0 .05 ) . ②GLS ,GAS and GRS were lower in mild ,moderate and severe group compared with control group ,decreasing along with the disease severity ( P ＜0 .01 or P ＜ 0 .05 ) . GCS in severe group was lower than that in control group ( P ＜0 .01 ) . ③GLS and GAS in severe group were lower than those in mild group ( all P ＜0 .05) .GRS in moderate and severe group were lower than that in mild group( all P ＜ 0 .05 ) ,GAS ,GRS in severe group was lower than those in moderate group ( P ＜0 .05) . ④T here was a mild correlation between GLS and A HI ( r ＝0 .342 , P ＜0 .01) ,GAS and A HI ( r＝0 .294 , P ＜0 .01) ,GRS and A HI ( r ＝ －0 .411 , P ＜0 .01 ) . T here was a mild correlation between GCS and three‐dimensional LVEF ( r＝ －0 .354 , P ＜0 .01 ) ,GAS and three‐dimensional LVEF ( r ＝ －0 .326 , P ＜0 .01) ,GRS and three‐dimensional LVEF ( r ＝0 .300 , P ＜0 .01) . Conclusions T he left ventricular myocardial systolic function is impaired in all patients with OSA HS even with normal LVEF and the dysfunction is aggravating with the disease severity . Ultrasonic three‐dimensional strain imaging technology can be used to detect the subclinical myocardial systolic dysfunction quantitatively in the early stage of OSA HS patients .
ABSTRACT
Objective To introduce a method of reducing the postoperative syndrome of the uvulopalatopharyngoplasty(UPPP). Method UPPP was performed for 23 patients with obstructive sleep apnea hypopnea syndrom operation(OSAHS). Before or after the operation, dexamethasone was injected in oropharynx to control the edema of the oropharynx which caused by UPPP. Results Less syndrome had been occurred in these patients. Conclusion The edema of the oropharynx which caused by UPPP can be controlled by injecting dexamethasone in oropharynx. It can reduce the risk of the UPPP, and make the operation safer and more efficient.